Cov khoom siv biomedical cuam tshuam nrog cov kab mob lom thiab siv los kuaj kab mob. Kev kho, kho thiab hloov cov ntaub so ntswg puas. Ib lub cev los yog ib hom khoom uas txhim kho nws txoj haujlwm.
Nyob rau hauv xyoo tas los no, nrog kev txhim kho txuas ntxiv ntawm tib neeg txoj kev ua neej nyob thiab kev ncua sij hawm nruab nrab ntawm lub neej, qhov kev thov rau cov ntaub ntawv biomedical tau loj hlob sai. Tib neeg txoj kev cog qoob loo yuav tsum tau tsim ib tus zuj zus thiab tsim sai sai rau txhua tus neeg mob txhawm rau txhawm rau txhawm rau kho lub sijhawm zoo tshaj plaws thiab txo tus neeg mob qhov mob. Txawm li cas los xij, cov txheej txheem kev ua haujlwm ib txwm muaj lub voj voog ntev thiab tus nqi siab, tshwj xeeb tshaj yog rau kev cog qoob loo lom nrog cov duab nyuaj uas nyuaj rau kev khiav lag luam thiab tswj nrog cov txheej txheem ib txwm muaj.
SLS technology los npaj cov ntaub ntawv biomedical
Cov ntaub ntawv biomedical npaj los ntawm SLS thev naus laus zis yog cov khoom siv biomedical polymer, biomedical hlau cov ntaub ntawv thiab biomedical composite cov ntaub ntawv. Cov ntaub ntawv kho mob no feem ntau yog siv hauv kev kho mob los ua qauv kho mob, cog thiab prostheses, thiab cov ntaub so ntswg engineering scaffolds.
1. Kev kho mob qauv
Qhov ntxov tshaj plaws ntawm SLS thev naus laus zis hauv kev lag luam biomedicine yog ua qauv kho mob los muab kev kho mob tsim thiab kev npaj kho mob thiab kev phais, simulation ntawm cov txheej txheem phais, thiab kev qhia kho mob. Craniomaxillofacial defect yog ib yam kab mob uas tshwm sim hauv kev kho phais, nrog rau qhov chaw nkhaus thiab ntau cov qauv hollow. Tsis muaj ib txoj hauv kev kho uas twb muaj lawm tuaj yeem ua tiav qhov zoo tshaj plaws ntawm tus neeg lub pob txha taub hau thiab lub puab tsaig, thiab tsuas tuaj yeem rov kho lub ntsej muag zoo nkauj xwb, uas tsis tuaj yeem ua tau raws li tus neeg mob qhov kev xav zoo nkauj. SLS thev naus laus zis los ua tus qauv pob txha taub hau tus kheej yog qhov ua tau zoo heev. Cov txheej txheem ua haujlwm tshwj xeeb yog:
① Cov khoom siv ua qauv. Xaiv ib qho tshuaj tua kab mob pob txha taub hau.
② CT scan. Lub CT scanner yog siv los ua qhov txuas txuas txuas txuas ntxiv ntawm cov pob txha taub hau, thiab cov duab tomographic tau raug xa mus rau qhov chaw ua haujlwm rov tsim kho thiab khaws cia hauv DICOM hom.
③ Peb-dimensional qauv reconstruction. Mimics software yog siv los nyeem cov ntawv DICOM hom ntawv. Los ntawm kev lees paub, kev rho tawm thiab peb-dimensional superposition ntawm cov pob txha hauv cheeb tsam, qhov peb-seem rov tsim kho ntawm cov qauv geometric ntawm pob txha taub hau tsis zoo yog ua tiav. Cov ntaub ntawv rov tsim dua yog tso tawm rau STL hom ntawv los ntawm CTM module.
④ SLS ceev prototyping. Siv MagicsRP qhov chaw txheej txheej software, cov ntaub ntawv STL cov ntaub ntawv yog txheej txheej ntawm qee lub sijhawm los tsim cov ntaub ntawv tomographic STL xav tau los ntawm SLS, thiab tom qab ntawd cov ntaub ntawv STL txheej txheej yog nkag mus rau SLS lub tshuab ua cov qauv. Cov kev tshawb fawb tau pom tias kev siv CT scanning, peb-dimensional qauv thiab SLS cov tswv yim los tsim cov phiaj xwm sib txawv rau cov neeg mob sib txawv, cov duab, qauv thiab qhov loj ntawm tus kheej cov qauv tsis zoo thiab cov qauv kho dua tshiab yog qhov zoo ib yam li cov qauv pob txha taub hau. , uas yog nyob rau hauv txoj kab nrog lub puab tsaig. Cov kev cai ntawm kev phais ntsej muag tuaj yeem siv rau kev kuaj mob ua ntej thiab kev npaj phais.
2. Implants thiab prostheses
Kev cog qoob loo thiab cov khoom siv prosthesis yog tsim los ntawm cov khoom siv roj ntsha sib xws nrog tib neeg lub cev, thiab tuaj yeem ua lub luag haujlwm hauv kev kho thiab rov ua haujlwm tom qab cog lossis hnav tib neeg lub cev. Los ntawm kev xav ntawm biomedical engineering, lub implanter yuav tsum ua tau raws li 3 yam hauv qab no:
① Muaj zog txhua yam los tiv thaiv lub cev qhov hnyav thiab cuam tshuam thaum ua haujlwm;
② Kev sib txuam ntawm tus kheej kom phim qhov chaw tsis xws luag thiab cov ntaub so ntswg ib puag ncig;
③ Cov ntaub so ntswg zoo sib xws. Txawm li cas los xij, cov cim uas twb muaj lawm tsis muaj qhov sib txuam ntawm tus kheej.
Txoj kev loj hlob sai ntawm cov khoom siv science, computer technology thiab SLS thev naus laus zis tau ua rau tus kheej tsim, kev tsim khoom sai thiab nrov ntawm cov cog cog.
Ob txoj kev siv los npaj lub cev complex muaj nyob rau hauv ntau: ua ntej, CT scan thiab peb-dimensional reconstruction yog siv kom tau cov qauv ntawm lub restoration, ces lub koom haum yog tsim los ntawm lub SLS technology, thiab thaum kawg lub dag complex lub cev yog tau. los ntawm cov txheej txheem reworking. Piv nrog rau cov txheej txheem tsim khoom ib txwm muaj, nws txuag lub sijhawm thiab cov nqi ntawm cov khoom siv, txo cov qib kev tsim khoom thiab cov nqi, thiab muab lub hauv paus rau kev txhawb nqa thiab kev siv SLS thev naus laus zis hauv kev lag luam biomedicine.
3. Cov ntaub so ntswg engineering scaffold
Tissue engineering yog ib qho kev qhuab qhia tshiab uas siv cov hauv paus ntsiab lus thiab cov txheej txheem ntawm engineering science thiab life science los tsim cov khoom siv roj ntsha hloov kho, tswj lossis txhim kho cov haujlwm ntawm cov ntaub so ntswg puas lossis cov kabmob. Biomaterials siv hauv cov ntaub so ntswg engineering scaffolds yuav tsum tau ua raws li cov hauv qab no:
① Cov txheej txheem peb-dimensional ntxeem tau network pab txhawb kev loj hlob ntawm tes thiab kev hloov pauv ntawm cov as-ham thiab metabolic pov tseg;
② Zoo biocompatibility, uas yog, tsis muaj kev pom tseeb cytotoxicity, inflammatory cov tshuaj tiv thaiv thiab tiv thaiv kab mob;
③ Tsim nyog biodegradability, thiab qhov degradation tus nqi sib tw rau kev loj hlob thiab kev loj hlob ntawm cov ntaub so ntswg tshiab;
④ Tsim nyog qhov chaw lub cev thiab cov khoom siv tshuaj lom neeg los pab txhawb lub cell adhesion, proliferation thiab sib txawv;
⑤ Qee yam khoom siv biomechanical tuaj yeem tswj tau qhov kev ruaj ntseg thiab kev ncaj ncees ntawm cov qauv thiab cov tsos ntawm ib puag ncig ntawm lub cev.
Cov ntaub ntawv siv rau cov ntaub so ntswg engineering scaffolds feem ntau suav nrog natural biomaterials, bioceramics thiab hluavtaws polymer cov ntaub ntawv. Cov ntaub so ntswg engineering Scaffolds tau txais los ntawm cov txheej txheem kev npaj ib txwm muaj xws li kev sib txuas ntawm fiber ntau, kev daws teeb meem leaching txoj kev, theem sib cais txoj kev, roj foaming txoj kev, thiab particle sintering txoj kev muaj cov neeg kho tshuab tsis zoo, tsis tshua muaj kev cuam tshuam ntawm pores, porosity thiab pore qauv Lub controllability yog tsis hloov tau.
SLS sai prototyping tshuab siv xaiv sintering ntawm polymers los yog polymer/bioceramic composites los tsim stents. Lub microstructure ntawm stent tuaj yeem tswj tau los ntawm kev kho cov txheej txheem SLS, thiab cov stents tau txais yog tag nrho cov qauv ntxeem tau.
SLS thev naus laus zis los npaj cov ntaub ntawv biomedical tuaj yeem tsis tsuas yog ua tiav tus kheej tsim thiab ua kom tau raws li tus neeg xav tau kev pab ntawm cov neeg mob sib txawv, tab sis kuj hloov kho lub microstructure thiab mechanical zog ntawm biomedical cov ntaub ntawv los ntawm kev kho lawv cov txheej txheem tsis thiab cov txheej txheem tom qab ua tiav. Txawm li cas los xij, cov khoom siv biomedical npaj los ntawm cov cuab yeej siv tshuab feem ntau muaj teeb meem tsis tshua muaj zog, cov khoom siv roj polymer / cov kabmob sib xyaw ua ke, uas tsis tuaj yeem ua tau cov khoom siv tshuab ntawm biomedical. Txawm li cas los xij, siv cov yam ntxwv ntawm SLS thev naus laus zis, nws yog qhov yooj yim los npaj cov ntaub ntawv ntxhib thiab ntxeem tau hlau uas tsim nyog rau kev ua haujlwm ntawm tes thiab kev loj hlob, tshwj xeeb tshaj yog cov khoom siv titanium thiab titanium alloy nrog cov khoom zoo heev biocompatibility thiab txhua yam khoom. Qhov no yuav yog SLS Technology yog ib qho tseem ceeb ntawm txoj kev loj hlob ntawm kev npaj cov ntaub ntawv biomedical.